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Predicting deleterious missense genetic variants via integrative supervised nonnegative matrix tri-factorization

Among an assortment of genetic variations, Missense are major ones which a small subset of them may led to the upset of the protein function and ultimately end in human diseases. Various machine learning methods were declared to differentiate deleterious and benign missense variants by means of a la...

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Detalles Bibliográficos
Autores principales: Arani, Asieh Amousoltani, Sehhati, Mohammadreza, Tabatabaiefar, Mohammad Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660898/
https://www.ncbi.nlm.nih.gov/pubmed/34887492
http://dx.doi.org/10.1038/s41598-021-03230-x