Novel Human Insulin Isoforms and Cα-Peptide Product in Islets of Langerhans and Choroid Plexus

Human insulin (INS) gene diverged from the ancestral genes of invertebrate and mammalian species millions of years ago. We previously found that mouse insulin gene (Ins2) isoforms are expressed in brain choroid plexus (ChP) epithelium cells, where insulin secretion is regulated by serotonin and not...

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Detalles Bibliográficos
Autores principales: Liu, Qing-Rong, Zhu, Min, Zhang, Pingbo, Mazucanti, Caio H., Huang, Nicholas S., Lang, Doyle L., Chen, Qinghua, Auluck, Pavan, Marenco, Stefano, O’Connell, Jennifer F., Ferrucci, Luigi, Chia, Chee W., Egan, Josephine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660980/
https://www.ncbi.nlm.nih.gov/pubmed/34649926
http://dx.doi.org/10.2337/db21-0198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660980/
https://www.ncbi.nlm.nih.gov/pubmed/34649926
http://dx.doi.org/10.2337/db21-0198

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