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Dynamic localization of DNA topoisomerase I and its functional relevance during Drosophila development

DNA topoisomerase I (Top1) maintains chromatin conformation during transcription. While Top1 is not essential in simple eukaryotic organisms such as yeast, it is required for the development of multicellular organisms. In fact, tissue and cell-type-specific functions of Top1 have been suggested in t...

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Detalles Bibliográficos
Autores principales: Huang, Wuqiang, Liu, Zhiping, Rong, Yikang S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661406/
https://www.ncbi.nlm.nih.gov/pubmed/34544118
http://dx.doi.org/10.1093/g3journal/jkab202