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Dynamic localization of DNA topoisomerase I and its functional relevance during Drosophila development
DNA topoisomerase I (Top1) maintains chromatin conformation during transcription. While Top1 is not essential in simple eukaryotic organisms such as yeast, it is required for the development of multicellular organisms. In fact, tissue and cell-type-specific functions of Top1 have been suggested in t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661406/ https://www.ncbi.nlm.nih.gov/pubmed/34544118 http://dx.doi.org/10.1093/g3journal/jkab202 |