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Variance-component-based meta-analysis of gene–environment interactions for rare variants
Complex diseases are often caused by interplay between genetic and environmental factors. Existing gene–environment interaction (G × E) tests for rare variants largely focus on detecting gene-based G × E effects in a single study; thus, their statistical power is limited by the sample size of the st...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661424/ https://www.ncbi.nlm.nih.gov/pubmed/34544119 http://dx.doi.org/10.1093/g3journal/jkab203 |