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Variance-component-based meta-analysis of gene–environment interactions for rare variants

Complex diseases are often caused by interplay between genetic and environmental factors. Existing gene–environment interaction (G × E) tests for rare variants largely focus on detecting gene-based G × E effects in a single study; thus, their statistical power is limited by the sample size of the st...

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Detalles Bibliográficos
Autores principales: Jin, Xiaoqin, Shi, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661424/
https://www.ncbi.nlm.nih.gov/pubmed/34544119
http://dx.doi.org/10.1093/g3journal/jkab203