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PseudoGA: cell pseudotime reconstruction based on genetic algorithm
Dynamic regulation of gene expression is often governed by progression through transient cell states. Bulk RNA-seq analysis can only detect average change in expression levels and is unable to identify this dynamics. Single cell RNA-seq presents an unprecedented opportunity that helps in placing the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661435/ https://www.ncbi.nlm.nih.gov/pubmed/34244782 http://dx.doi.org/10.1093/nar/gkab457 |