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Cannabidiol inhibits SARS‐Cov‐2 spike (S) protein‐induced cytotoxicity and inflammation through a PPARγ‐dependent TLR4/NLRP3/Caspase‐1 signaling suppression in Caco‐2 cell line

Given the abundancy of angiotensin converting enzyme 2 (ACE‐2) receptors density, beyond the lung, the intestine is considered as an alternative site of infection and replication for severe acute respiratory syndrome by coronavirus type 2 (SARS‐CoV‐2). Cannabidiol (CBD) has recently been proposed in...

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Detalles Bibliográficos
Autores principales: Corpetti, Chiara, Del Re, Alessandro, Seguella, Luisa, Palenca, Irene, Rurgo, Sara, De Conno, Barbara, Pesce, Marcella, Sarnelli, Giovanni, Esposito, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662250/
https://www.ncbi.nlm.nih.gov/pubmed/34643000
http://dx.doi.org/10.1002/ptr.7302