Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischemia

The bioactive lipid intermediate palmitoyl CoA (PCoA) can inhibit mitochondrial ADP/ATP transport, though the physiological relevance of this regulation remains unclear. We questioned whether myocardial ischemia provides a pathological setting in which PCoA regulation of ADP/ATP transport would be b...

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Detalles Bibliográficos
Autores principales: Kerr, M., Dennis, K. M. J. H., Carr, C. A., Fuller, W., Berridge, G., Rohling, S., Aitken, C. L., Lopez, C., Fischer, R., Miller, J. J., Clarke, K., Tyler, D. J., Heather, L. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662312/
https://www.ncbi.nlm.nih.gov/pubmed/34318967
http://dx.doi.org/10.1096/fj.202100394R

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