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Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic

The worldwide outbreak of SARS-CoV-2 infection has necessitated mandatory use of face masks, personal protective equipment and intake of a healthy diet for immunity boosting. As per WHO's recommendation, continuous use of masks has been proven effective in decreasing the SARS-CoV-2 infection ra...

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Autores principales: Avinash Patil, Nikhil, Macchindra Gore, Prakash, Shanmugrajan, Dhivya, Patil, Harshal, Kudav, Mahesh, Kandasubramanian, Balasubramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662388/
https://www.ncbi.nlm.nih.gov/pubmed/34956609
http://dx.doi.org/10.1098/rsfs.2021.0040
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author Avinash Patil, Nikhil
Macchindra Gore, Prakash
Shanmugrajan, Dhivya
Patil, Harshal
Kudav, Mahesh
Kandasubramanian, Balasubramanian
author_facet Avinash Patil, Nikhil
Macchindra Gore, Prakash
Shanmugrajan, Dhivya
Patil, Harshal
Kudav, Mahesh
Kandasubramanian, Balasubramanian
author_sort Avinash Patil, Nikhil
collection PubMed
description The worldwide outbreak of SARS-CoV-2 infection has necessitated mandatory use of face masks, personal protective equipment and intake of a healthy diet for immunity boosting. As per WHO's recommendation, continuous use of masks has been proven effective in decreasing the SARS-CoV-2 infection rate. The present study reports on the bacterial filtration efficacy (BFE) of a novel 4-ply functionalized non-woven face mask. We synthesized a polypropylene-based fabric with inner layers of melt-blown fine fibres coated with polylactic acid and immune-boosting herbal phytochemicals. Experimental studies on the synthesized face mask demonstrated a BFE of greater than 99% against Staphylococcus aureus (a bacterium species frequently found in mammalian respiratory tract). A thorough computational analysis using LibDock algorithm demonstrated an effective docking performance of herbal phytochemicals against harmful virus structures. More importantly, the face mask also showed sufficient and stable breathability as per regulatory standards. A breathing resistance of 30 Pa at an aerosol flow rate of 30 l h(−1) was reported under standard temperature and pressure conditions, indicating a high potential for real-world applications.
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spelling pubmed-86623882021-12-23 Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic Avinash Patil, Nikhil Macchindra Gore, Prakash Shanmugrajan, Dhivya Patil, Harshal Kudav, Mahesh Kandasubramanian, Balasubramanian Interface Focus Articles The worldwide outbreak of SARS-CoV-2 infection has necessitated mandatory use of face masks, personal protective equipment and intake of a healthy diet for immunity boosting. As per WHO's recommendation, continuous use of masks has been proven effective in decreasing the SARS-CoV-2 infection rate. The present study reports on the bacterial filtration efficacy (BFE) of a novel 4-ply functionalized non-woven face mask. We synthesized a polypropylene-based fabric with inner layers of melt-blown fine fibres coated with polylactic acid and immune-boosting herbal phytochemicals. Experimental studies on the synthesized face mask demonstrated a BFE of greater than 99% against Staphylococcus aureus (a bacterium species frequently found in mammalian respiratory tract). A thorough computational analysis using LibDock algorithm demonstrated an effective docking performance of herbal phytochemicals against harmful virus structures. More importantly, the face mask also showed sufficient and stable breathability as per regulatory standards. A breathing resistance of 30 Pa at an aerosol flow rate of 30 l h(−1) was reported under standard temperature and pressure conditions, indicating a high potential for real-world applications. The Royal Society 2021-12-10 /pmc/articles/PMC8662388/ /pubmed/34956609 http://dx.doi.org/10.1098/rsfs.2021.0040 Text en © 2021 The Author(s) https://royalsociety.org/-/media/journals/author/Licence-to-Publish-20062019-final.pdfhttps://royalsociety.org/journals/ethics-policies/data-sharing-mining/Published by the Royal Society. All rights reserved.
spellingShingle Articles
Avinash Patil, Nikhil
Macchindra Gore, Prakash
Shanmugrajan, Dhivya
Patil, Harshal
Kudav, Mahesh
Kandasubramanian, Balasubramanian
Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic
title Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic
title_full Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic
title_fullStr Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic
title_full_unstemmed Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic
title_short Functionalized non-woven surfaces for combating the spread of the COVID-19 pandemic
title_sort functionalized non-woven surfaces for combating the spread of the covid-19 pandemic
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662388/
https://www.ncbi.nlm.nih.gov/pubmed/34956609
http://dx.doi.org/10.1098/rsfs.2021.0040
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