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Immune-Related Adverse Events in PD-1 Treated Melanoma and Impact Upon Anti-Tumor Efficacy: A Real World Analysis
BACKGROUND: Anti-PD-1 immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of melanoma by producing durable long-term responses in a subset of patients. ICI-treated patients develop unique toxicities - immune related adverse events (irAEs) – that arise from unrestrained immune...
Autores principales: | Bastacky, Melissa L., Wang, Hong, Fortman, Dylan, Rahman, Zahra, Mascara, Gerard P., Brenner, Timothy, Najjar, Yana G., Luke, Jason J., Kirkwood, John M., Zarour, Hassane M., Davar, Diwakar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662734/ https://www.ncbi.nlm.nih.gov/pubmed/34900695 http://dx.doi.org/10.3389/fonc.2021.749064 |
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