The IRF2/CENP-N/AKT signaling axis promotes proliferation, cell cycling and apoptosis resistance in nasopharyngeal carcinoma cells by increasing aerobic glycolysis

BACKGROUND: Centromere protein N (CENP-N) has been reported to be highly expressed in malignancies, but its role and mechanism in nasopharyngeal carcinoma (NPC) are unknown. METHODS: Abnormal CENP-N expression from NPC microarrays of GEO database was analyzed. CENP-N expression level was confirmed i...

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Detalles Bibliográficos
Autores principales: Qi, Cheng-Lin, Huang, Mao-Ling, Zou, You, Yang, Rui, Jiang, Yang, Sheng, Jian-Fei, Kong, Yong-Gang, Tao, Ze-Zhang, Feng, Hong-Yan, Hua, Qing-Quan, Bu, Li-Hong, Chen, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662847/
https://www.ncbi.nlm.nih.gov/pubmed/34893086
http://dx.doi.org/10.1186/s13046-021-02191-3

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