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Long non-coding RNA NORAD/miR-224-3p/MTDH axis contributes to CDDP resistance of esophageal squamous cell carcinoma by promoting nuclear accumulation of β-catenin

BACKGROUND: Cis-diamminedichloro-platinum (CDDP)-based chemotherapy regimens are the most predominant treatment strategies for patients with esophageal squamous cell carcinoma (ESCC). Dysregulated long non-coding RNAs (lncRNAs) contribute to CDDP resistance, which results in treatment failure in ESC...

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Detalles Bibliográficos
Autores principales: Jia, Yunlong, Tian, Cong, Wang, Hongyan, Yu, Fan, Lv, Wei, Duan, Yuqing, Cheng, Zishuo, Wang, Xuexiao, Wang, Yu, Liu, Tianxu, Wang, Jiali, Liu, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662861/
https://www.ncbi.nlm.nih.gov/pubmed/34893064
http://dx.doi.org/10.1186/s12943-021-01455-y