Increased Angiotensin-Converting Enzyme 2 and Loss of Alveolar Type II Cells in COVID-19–related Acute Respiratory Distress Syndrome

Rationale: ACE2 (angiotensin-converting enzyme 2), the entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is expressed in type 2 alveolar epithelial cells (AT2) that may play key roles in postinjury repair. An imbalance between ACE2 and ACE has also been hypothesized to...

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Detalles Bibliográficos
Autores principales: Gerard, Ludovic, Lecocq, Marylene, Bouzin, Caroline, Hoton, Delphine, Schmit, Gregory, Pereira, Joao Pinto, Montiel, Virginie, Plante-Bordeneuve, Thomas, Laterre, Pierre-François, Pilette, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663012/
https://www.ncbi.nlm.nih.gov/pubmed/34449302
http://dx.doi.org/10.1164/rccm.202012-4461OC

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