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Regulatory T Cell–Derived TRAIL Is Not Required for Peripheral Tolerance
TRAIL (Tnfsf10/TRAIL/CD253/Apo2L) is an important immune molecule that mediates apoptosis. TRAIL can play key roles in regulating cell death in the tumor and autoimmune microenvironments. However, dissecting TRAIL function remains difficult because of the lack of optimal models. We have now generate...
Autores principales: | Dadey, Rebekah E., Grebinoski, Stephanie, Zhang, Qianxia, Brunazzi, Erin A., Burton, Amanda, Workman, Creg J., Vignali, Dario A. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663370/ https://www.ncbi.nlm.nih.gov/pubmed/33483333 http://dx.doi.org/10.4049/immunohorizons.2000098 |
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