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Regulatory T Cell–Derived TRAIL Is Not Required for Peripheral Tolerance

TRAIL (Tnfsf10/TRAIL/CD253/Apo2L) is an important immune molecule that mediates apoptosis. TRAIL can play key roles in regulating cell death in the tumor and autoimmune microenvironments. However, dissecting TRAIL function remains difficult because of the lack of optimal models. We have now generate...

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Detalles Bibliográficos
Autores principales: Dadey, Rebekah E., Grebinoski, Stephanie, Zhang, Qianxia, Brunazzi, Erin A., Burton, Amanda, Workman, Creg J., Vignali, Dario A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663370/
https://www.ncbi.nlm.nih.gov/pubmed/33483333
http://dx.doi.org/10.4049/immunohorizons.2000098

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