Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency

BACKGROUND: LNK/SH2B3 inhibits Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling by hematopoietic cytokine receptors. Genome-wide association studies have shown association of a common single nucleotide polymorphism in LNK (R262W, T allele) with neutrophilia, thrombo...

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Detalles Bibliográficos
Autores principales: Dou, Huijuan, Kotini, Andriana, Liu, Wenli, Fidler, Trevor, Endo-Umeda, Kaori, Sun, Xiaoli, Olszewska, Malgorzata, Xiao, Tong, Abramowicz, Sandra, Yalcinkaya, Mustafa, Hardaway, Brian, Tsimikas, Sotirios, Que, Xuchu, Bick, Alexander, Emdin, Conor, Natarajan, Pradeep, Papapetrou, Eirini P., Witztum, Joseph L., Wang, Nan, Tall, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663540/
https://www.ncbi.nlm.nih.gov/pubmed/34846914
http://dx.doi.org/10.1161/CIRCULATIONAHA.121.056414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663540/
https://www.ncbi.nlm.nih.gov/pubmed/34846914
http://dx.doi.org/10.1161/CIRCULATIONAHA.121.056414

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