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Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19

COVID-19 is caused by SARS-CoV-2 (SC2) and is more prevalent and severe in elderly and patients with comorbid diseases (CM). Because chitinase 3-like-1 (CHI3L1) is induced during aging and CM, the relationships between CHI3L1 and SC2 were investigated. Here, we demonstrate that CHI3L1 is a potent st...

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Detalles Bibliográficos
Autores principales:	Kamle, Suchitra, Ma, Bing, He, Chuan Hua, Akosman, Bedia, Zhou, Yang, Lee, Chang-Min, El-Deiry, Wafik S., Huntington, Kelsey, Liang, Olin, Machan, Jason T., Kang, Min-Jong, Shin, Hyeon Jun, Mizoguchi, Emiko, Lee, Chun Geun, Elias, Jack A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663553/ https://www.ncbi.nlm.nih.gov/pubmed/34747367 http://dx.doi.org/10.1172/jci.insight.148749

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