Identification of an ATP/P2X7/mast cell pathway mediating ozone-induced bronchial hyperresponsiveness

Ozone is a highly reactive environmental pollutant with well-recognized adverse effects on lung health. Bronchial hyperresponsiveness (BHR) is one consequence of ozone exposure, particularly for individuals with underlying lung disease. Our data demonstrated that ozone induced substantial ATP releas...

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Detalles Bibliográficos
Autores principales: Kong, Xiaomei, Bennett, William C., Jania, Corey M., Chason, Kelly D., German, Zachary, Adouli, Jennifer, Budney, Samuel D., Oby, Brandon T., van Heusden, Catharina, Lazarowski, Eduardo R., Jaspers, Ilona, Randell, Scott H., Hedgespeth, Barry A., Cruse, Glenn, Hua, Xiaoyang, Schworer, Stephen A., Smith, Gregory J., Kelada, Samir N.P., Tilley, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663556/
https://www.ncbi.nlm.nih.gov/pubmed/34546976
http://dx.doi.org/10.1172/jci.insight.140207

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