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Therapeutic radiation exposure of the abdomen during childhood induces chronic adipose tissue dysfunction
BACKGROUND: Childhood cancer survivors who received abdominal radiotherapy (RT) or total body irradiation (TBI) are at increased risk for cardiometabolic disease, but the underlying mechanisms are unknown. We hypothesize that RT-induced adipose tissue dysfunction contributes to the development of ca...
Autores principales: | Huang, Xiaojing, Maguire, Olivia A., Walker, Jeanne M., Jiang, Caroline S., Carroll, Thomas S., Luo, Ji-Dung, Tonorezos, Emily, Friedman, Danielle Novetsky, Cohen, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663557/ https://www.ncbi.nlm.nih.gov/pubmed/34554929 http://dx.doi.org/10.1172/jci.insight.153586 |
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