HuR/Cx40 downregulation causes coronary microvascular dysfunction in type 2 diabetes

Patients with diabetes with coronary microvascular disease (CMD) exhibit higher cardiac mortality than patients without CMD. However, the molecular mechanism by which diabetes promotes CMD is poorly understood. RNA-binding protein human antigen R (HuR) is a key regulator of mRNA stability and transl...

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Detalles Bibliográficos
Autores principales: Si, Rui, Cabrera, Jody Tori O., Tsuji-Hosokawa, Atsumi, Guo, Rui, Watanabe, Makiko, Gao, Lei, Lee, Yun Sok, Moon, Jae-Su, Scott, Brian T., Wang, Jian, Ashton, Anthony W., Rao, Jaladanki N., Wang, Jian-Ying, Yuan, Jason X.-J., Makino, Ayako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663561/
https://www.ncbi.nlm.nih.gov/pubmed/34747371
http://dx.doi.org/10.1172/jci.insight.147982

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