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Role of endothelial cells in pulmonary fibrosis via SREBP2 activation

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited treatment options. Despite endothelial cells (ECs) comprising 30% of the lung cellular composition, the role of EC dysfunction in pulmonary fibrosis (PF) remains unclear. We hypothesize that sterol regulatory element-bind...

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Detalles Bibliográficos
Autores principales:	Martin, Marcy, Zhang, Jiao, Miao, Yifei, He, Ming, Kang, Jian, Huang, Hsi-Yuan, Chou, Chih-Hung, Huang, Tse-Shun, Hong, Hsiao-Chin, Su, Shu-Han, Wong, Simon S., Harper, Rebecca L., Wang, Lingli, Bhattacharjee, Rakesh, Huang, Hsien-Da, Chen, Zhen Bouman, Malhotra, Atul, Rabinovitch, Marlene, Hagood, James S., Shyy, John Y-J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663776/ https://www.ncbi.nlm.nih.gov/pubmed/34806652 http://dx.doi.org/10.1172/jci.insight.125635

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