Irreversible depletion of intestinal CD4(+) T cells is associated with T cell activation during chronic HIV infection

HIV infection in the human gastrointestinal (GI) tract is thought to be central to HIV progression, but knowledge of this interaction is primarily limited to cohorts within Westernized countries. Here, we present a large cohort recruited from high HIV endemic areas in South Africa and found that peo...

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Detalles Bibliográficos
Autores principales: Asowata, Osaretin E., Singh, Alveera, Ngoepe, Abigail, Herbert, Nicholas, Fardoos, Rabiah, Reddy, Kavidha, Zungu, Yenzekile, Nene, Faith, Mthabela, Ntombifuthi, Ramjit, Dirhona, Karim, Farina, Govender, Katya, Ndung’u, Thumbi, Porterfield, J. Zachary, Adamson, John H., Madela, Fusi G., Manzini, Vukani T., Anderson, Frank, Leslie, Alasdair, Kløverpris, Henrik N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663780/
https://www.ncbi.nlm.nih.gov/pubmed/34618690
http://dx.doi.org/10.1172/jci.insight.146162

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