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Human nasal wash RNA-Seq reveals distinct cell-specific innate immune responses in influenza versus SARS-CoV-2

BACKGROUND: Influenza A virus (IAV) and SARS-CoV-2 are pandemic viruses causing millions of deaths, yet their clinical manifestations are distinctly different. METHODS: With the hypothesis that upper airway immune and epithelial cell responses are also distinct, we performed single-cell RNA sequenci...

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Detalles Bibliográficos
Autores principales:	Gao, Kevin M., Derr, Alan G., Guo, Zhiru, Nündel, Kerstin, Marshak-Rothstein, Ann, Finberg, Robert W., Wang, Jennifer P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Clinical Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663782/ https://www.ncbi.nlm.nih.gov/pubmed/34618691 http://dx.doi.org/10.1172/jci.insight.152288

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