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Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report
RATIONALE: Necrotizing sarcoid granulomatosis (NSG) has recently been termed “sarcoidosis with NSG pattern” for the disease entity representing nodular sarcoidosis with granulomatous pulmonary angiitis. It is characterized by sarcoid-like granulomas, vasculitis, and a variable degree of necrosis. It...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663815/ https://www.ncbi.nlm.nih.gov/pubmed/34889304 http://dx.doi.org/10.1097/MD.0000000000028208 |
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author | Kim, Jun Hyeok Nam, Bo Da Hwang, Jung Hwa Kim, Dong Won Kim, Ki-Up Park, Young Woo |
author_facet | Kim, Jun Hyeok Nam, Bo Da Hwang, Jung Hwa Kim, Dong Won Kim, Ki-Up Park, Young Woo |
author_sort | Kim, Jun Hyeok |
collection | PubMed |
description | RATIONALE: Necrotizing sarcoid granulomatosis (NSG) has recently been termed “sarcoidosis with NSG pattern” for the disease entity representing nodular sarcoidosis with granulomatous pulmonary angiitis. It is characterized by sarcoid-like granulomas, vasculitis, and a variable degree of necrosis. Its rarity and nonspecific clinical symptoms can easily lead to misdiagnosis or delayed diagnosis. PATIENT CONCERNS: We report a 67-year-old female with a biopsy-confirmed sarcoidosis with NSG pattern mimicking pulmonary malignancy on initial chest computed tomography scan. DIAGNOSES: Sarcoidosis with NSG pattern. INTERVENTIONS: The patient underwent video-assisted thoracoscopic surgery with a lung biopsy. No further treatment was performed after the lung biopsy. OUTCOMES: Follow-up imaging studies revealed spontaneous regression of the disease after 2 months. LESSONS: Awareness of this rare benign disease entity and overlapping radiologic manifestations with pulmonary malignancy or other granulomatous diseases can be helpful for making a precise diagnosis with a better differential diagnosis. |
format | Online Article Text |
id | pubmed-8663815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-86638152021-12-13 Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report Kim, Jun Hyeok Nam, Bo Da Hwang, Jung Hwa Kim, Dong Won Kim, Ki-Up Park, Young Woo Medicine (Baltimore) 6800 RATIONALE: Necrotizing sarcoid granulomatosis (NSG) has recently been termed “sarcoidosis with NSG pattern” for the disease entity representing nodular sarcoidosis with granulomatous pulmonary angiitis. It is characterized by sarcoid-like granulomas, vasculitis, and a variable degree of necrosis. Its rarity and nonspecific clinical symptoms can easily lead to misdiagnosis or delayed diagnosis. PATIENT CONCERNS: We report a 67-year-old female with a biopsy-confirmed sarcoidosis with NSG pattern mimicking pulmonary malignancy on initial chest computed tomography scan. DIAGNOSES: Sarcoidosis with NSG pattern. INTERVENTIONS: The patient underwent video-assisted thoracoscopic surgery with a lung biopsy. No further treatment was performed after the lung biopsy. OUTCOMES: Follow-up imaging studies revealed spontaneous regression of the disease after 2 months. LESSONS: Awareness of this rare benign disease entity and overlapping radiologic manifestations with pulmonary malignancy or other granulomatous diseases can be helpful for making a precise diagnosis with a better differential diagnosis. Lippincott Williams & Wilkins 2021-12-10 /pmc/articles/PMC8663815/ /pubmed/34889304 http://dx.doi.org/10.1097/MD.0000000000028208 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 6800 Kim, Jun Hyeok Nam, Bo Da Hwang, Jung Hwa Kim, Dong Won Kim, Ki-Up Park, Young Woo Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report |
title | Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report |
title_full | Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report |
title_fullStr | Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report |
title_full_unstemmed | Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report |
title_short | Necrotizing sarcoid granulomatosis simulating pulmonary malignancy: A case report |
title_sort | necrotizing sarcoid granulomatosis simulating pulmonary malignancy: a case report |
topic | 6800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663815/ https://www.ncbi.nlm.nih.gov/pubmed/34889304 http://dx.doi.org/10.1097/MD.0000000000028208 |
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