Risk factors for bile duct injury after laparoscopic cholecystectomy: A protocol for systematic review and meta-analysis

BACKGROUND: Bile duct injury (BDI) is one of the serious complications in laparoscopic cholecystectomy (LC), but there is currently a lack of systematic review of risk factors related to BDI after LC. This study conducts meta-analysis on the risk factors related to bile duct injury after LC, the purpose is to provide reference basis for preventing and reducing BDI after LC. METHODS: Using the Computer to retrieve of Chinese and English databases such as CNKI, WANFANG Data, the VIP Network, PubMed, Embase, the Cochrane Library, etc. The time is from the establishment of each database until August 2021. A case–control study is selected that is related to the risk factors of BDI after LC. This meta-analysis using RevMan 5.4 and State 12.0 software is performed after two researchers independently sift through the literature, extract the data, and evaluate the bias risk included in the study. RESULTS: The risk factors related to BDI after LC will be analyzed by systematic review. CONCLUSION: The conclusion of this study will play an important role in reducing BDI after LC. OSF REGISTRATION: DOI 10.17605/OSF.IO/2B3K9, the registration URL is https://osf.io/2b3k9.