Cargando…

TGF-β: The missing link in obesity-associated airway diseases?

Obesity is emerging as a global public health epidemic. The co-morbidities associated with obesity significantly contribute to reduced quality of life, mortality, and global healthcare burden. Compared to other asthma comorbidities, obesity prominently engenders susceptibility to inflammatory airway...

Descripción completa

Detalles Bibliográficos
Autores principales:	Woo, Joanna, Koziol-White, Cynthia, Panettieri, Reynold, Jude, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663968/ https://www.ncbi.nlm.nih.gov/pubmed/34909651 http://dx.doi.org/10.1016/j.crphar.2021.100016

Ejemplares similares

Dexamethasone rescues TGF-β1-mediated β(2)-adrenergic receptor dysfunction and attenuates phosphodiesterase 4D expression in human airway smooth muscle cells
por: Chung, Elena, et al.
Publicado: (2020)

Rhinovirus induces airway remodeling: what are the physiological consequences?
por: Spector, Cassandra, et al.
Publicado: (2023)

Modulation of airway hyperresponsiveness by rhinovirus exposure
por: Lo, Dennis, et al.
Publicado: (2018)

The Bronchoprotective Effects of Dual Pharmacology, Muscarinic Receptor Antagonist and β(2) Adrenergic Receptor Agonist Navafenterol in Human Small Airways
por: Jude, Joseph Antony, et al.
Publicado: (2023)

Airway Smooth Muscle–Specific Transcriptomic Signatures of Glucocorticoid Exposure
por: Kan, Mengyuan, et al.
Publicado: (2019)

Epinephrine evokes shortening of human airway smooth muscle cells following β(2) adrenergic receptor desensitization
por: Deeney, Brian T., et al.
Publicado: (2022)

An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling
por: Ghosh, Arnab, et al.
Publicado: (2020)

FFAR1 activation attenuates histamine-induced myosin light chain phosphorylation and cortical tension development in human airway smooth muscle cells
por: Xu, Shengjie, et al.
Publicado: (2020)

CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids
por: Kan, Mengyuan, et al.
Publicado: (2022)

Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma
por: Himes, Blanca E., et al.
Publicado: (2015)

A fungal protease allergen provokes airway hyperresponsiveness in asthma
por: Balenga, Nariman A., et al.
Publicado: (2015)

MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells
por: Dileepan, Mythili, et al.
Publicado: (2014)

Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?
por: Amrani, Yassine, et al.
Publicado: (2000)

The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR
por: Huang, Jessie, et al.
Publicado: (2020)

Multiorgan Damage in Patients With COVID-19: Is the TGF-β/BMP Pathway the Missing Link?
por: Carlson, F. Roy, et al.
Publicado: (2020)

Inhibition of PI3K promotes dilation of human small airways in a rho kinase‐dependent manner
por: Koziol‐White, Cynthia J, et al.
Publicado: (2016)

Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma
por: Gupta, Manveen K., et al.
Publicado: (2015)

Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype
por: Jude, Joseph A., et al.
Publicado: (2012)

Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling
por: Wang, Ruping, et al.
Publicado: (2022)

Bronchoconstriction: a potential missing link in airway remodelling
por: O'Sullivan, Michael J., et al.
Publicado: (2020)

Salicylic acid amplifies Carbachol-induced bronchoconstriction in human precision-cut lung slices
por: Jude, Joseph, et al.
Publicado: (2019)

Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans
por: Sun, Yan, et al.
Publicado: (2015)

MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells
por: Dileepan, Mythili, et al.
Publicado: (2016)

CFTR dysfunction in smooth muscle drives TGFβ dependent airway hyperreactivity
por: Kramer, Elizabeth L., et al.
Publicado: (2023)

Profile of aclidinium bromide in the treatment of chronic obstructive pulmonary disease
por: Sims, Michael W, et al.
Publicado: (2011)

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage
por: Velalopoulou, Anastasia, et al.
Publicado: (2017)

Obesity and Asthma: A Missing Link
por: Gomez-Llorente, Mª Amelia, et al.
Publicado: (2017)

Occupational Exposures in Rheumatoid Arthritis-related Airway Disease: A Missing Link?
por: Lee, Cathryn T., et al.
Publicado: (2022)

The Missing Link: Studying the Alternative TGF-β Pathway Provides a Unifying Theory for Different Components of Diabetic Nephropathy
por: Zheng, Xiaoyi, et al.
Publicado: (2015)

Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-α and dexamethasone
por: Tirumurugaan, Krishnaswamy G, et al.
Publicado: (2008)

Reply: Occupational Exposures in Rheumatoid Arthritis-related Airway Disease: A Missing Link?
por: Matson, Scott M., et al.
Publicado: (2022)

Obesity and Cancer: 27-Hydroxycholesterol, the Missing Link
por: Asghari, Arvand, et al.
Publicado: (2020)

Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization
por: Atochina, Elena N, et al.
Publicado: (2003)

Anaphylatoxin C3a receptors in asthma
por: Ali, Hydar, et al.
Publicado: (2005)

Reviewer acknowledgement 2012
por: Lötvall, Jan, et al.
Publicado: (2013)

Reviewer acknowledgement 2013
por: Lötvall, Jan, et al.
Publicado: (2014)

Reviewer acknowledgement 2015
por: Lötvall, Jan, et al.
Publicado: (2016)

Reviewer acknowledgement 2014
por: Lötvall, Jan, et al.
Publicado: (2015)

Thank you and farewell after 15 years editing respiratory research
por: Lotvall, Jan, et al.
Publicado: (2018)

TGF-β sensitivity is determined by N-linked glycosylation of the type II TGF-β receptor
por: Kim, Young-Woong, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_oii425kpkrkq8v16ctuu5gjr7n