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Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans
Zickler et al. describe SARS-CoV-2 RNA in post-mortem samples of human adipose tissue. In the hamster model, SARS-CoV-2 propagation in adipose tissue leads to specific changes in lipid metabolism, which are reflected in lipidome patterns of hamster and human plasma.
Autores principales: | Zickler, Martin, Stanelle-Bertram, Stephanie, Ehret, Sandra, Heinrich, Fabian, Lange, Philine, Schaumburg, Berfin, Kouassi, Nancy Mounogou, Beck, Sebastian, Jaeckstein, Michelle Y., Mann, Oliver, Krasemann, Susanne, Schroeder, Maria, Jarczak, Dominik, Nierhaus, Axel, Kluge, Stefan, Peschka, Manuela, Schlüter, Hartmut, Renné, Thomas, Pueschel, Klaus, Kloetgen, Andreas, Scheja, Ludger, Ondruschka, Benjamin, Heeren, Joerg, Gabriel, Guelsah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663969/ https://www.ncbi.nlm.nih.gov/pubmed/34895500 http://dx.doi.org/10.1016/j.cmet.2021.12.002 |
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