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SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells

Sentrin-specific protease (SENP) 2 has been suggested as a possible novel drug target for the treatment of obesity and type 2 diabetes mellitus after observations of a palmitate-induced increase in SENP2 that lead to increased fatty acid oxidation and improved insulin sensitivity in skeletal muscle...

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Detalles Bibliográficos
Autores principales: Lund, Jenny, Krapf, Solveig A., Sistek, Medina, Bakke, Hege G., Bartesaghi, Stefano, Peng, Xiao-Rong, Rustan, Arild C., Thoresen, G. Hege, Kase, Eili T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663970/
https://www.ncbi.nlm.nih.gov/pubmed/34909683
http://dx.doi.org/10.1016/j.crphar.2021.100061