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From dissection of fibrotic pathways to assessment of drug interactions to reduce cardiac fibrosis and heart failure
Cardiac fibrosis is characterized by extracellular matrix deposition in the cardiac interstitium, and this contributes to cardiac contractile dysfunction and progression of heart failure. The main players involved in this process are the cardiac fibroblasts, which, in the presence of pro-inflammator...
Autores principales: | Garoffolo, Gloria, Pesce, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663973/ https://www.ncbi.nlm.nih.gov/pubmed/34909666 http://dx.doi.org/10.1016/j.crphar.2021.100036 |
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