ATP citrate lyase inhibitor Bempedoic Acid alleviate long term HFD induced NASH through improvement in glycemic control, reduction of hepatic triglycerides & total cholesterol, modulation of inflammatory & fibrotic genes and improvement in NAS score

Non-alcoholic fatty liver disease (NAFLD) and Non-alcoholic steatohepatitis (NASH) are chronic liver disorders, the prevalence of which is increasing worldwide. Long term High Fat Diet (HFD) induced NASH animal models closely mimic the characteristics of human NASH and hence used by investigators as...

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Detalles Bibliográficos
Autores principales: Sanjay, K.V., Vishwakarma, Santosh, Zope, Bharat Ravindra, Mane, Vishal Subhash, Mohire, Sunil, Dhakshinamoorthy, Saravanakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663992/
https://www.ncbi.nlm.nih.gov/pubmed/34909677
http://dx.doi.org/10.1016/j.crphar.2021.100051

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