Cargando…

KDM4B promotes acute myeloid leukemia associated with AML1‐ETO by regulating chromatin accessibility

Epigenetic alterations of chromatin structure affect chromatin accessibility and collaborate with genetic alterations in the development of cancer. Lysine demethylase 4B (KDM4B) has been identified as a JmjC domain‐containing epigenetic modifier that possesses histone demethylase activity. Although...

Descripción completa

Detalles Bibliográficos
Autores principales: Ueda, Takeshi, Kanai, Akinori, Komuro, Akiyoshi, Amano, Hisayuki, Ota, Kazushige, Honda, Masahiko, Kawazu, Masahito, Okada, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664044/
https://www.ncbi.nlm.nih.gov/pubmed/34938963
http://dx.doi.org/10.1096/fba.2021-00030