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A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system

OBJECTIVES: This study attempts to explore a novel peripheral lung stereotactic body radiotherapy (SBRT) planning technique that can balance the pros and cons of three‐dimensional conformal radiotherapy (CRT) and intensity‐modulated radiation therapy (IMRT) / volumetric modulated arc therapy (VMAT)....

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Autores principales: Duan, YanHua, Zhou, LiJun, Wang, Hao, Chen, Hua, Gu, HengLe, Shao, Yan, Feng, AiHui, Huang, Ying, Fu, XiaoLong, Yue, Ning Jeff, Ma, Kui, Kong, Qing, Xu, ZhiYong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664147/
https://www.ncbi.nlm.nih.gov/pubmed/34699670
http://dx.doi.org/10.1002/acm2.13461
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author Duan, YanHua
Zhou, LiJun
Wang, Hao
Chen, Hua
Gu, HengLe
Shao, Yan
Feng, AiHui
Huang, Ying
Fu, XiaoLong
Yue, Ning Jeff
Ma, Kui
Kong, Qing
Xu, ZhiYong
author_facet Duan, YanHua
Zhou, LiJun
Wang, Hao
Chen, Hua
Gu, HengLe
Shao, Yan
Feng, AiHui
Huang, Ying
Fu, XiaoLong
Yue, Ning Jeff
Ma, Kui
Kong, Qing
Xu, ZhiYong
author_sort Duan, YanHua
collection PubMed
description OBJECTIVES: This study attempts to explore a novel peripheral lung stereotactic body radiotherapy (SBRT) planning technique that can balance the pros and cons of three‐dimensional conformal radiotherapy (CRT) and intensity‐modulated radiation therapy (IMRT) / volumetric modulated arc therapy (VMAT). METHODS: Treatment plans were retrospectively designed based on CRT, IMRT, VMAT, and the proposed CRT‐IMRT‐combined (Co‐CRIM) techniques using Pinnacle treatment planning system (TPS) for 20 peripheral lung cancer patients. Co‐CRIM used an inverse optimization algorithm available in Pinnacle TPS. To develop a Co‐CRIM plan, the number of segments in each field was limited to one, the minimum segment area was set to the internal target volume (ITV), and the minimum monitor units (MU) of the segment was the quotient of fractional dose divided by twice the number of total fields. The performance of Co‐CRIM was then compared with other techniques. RESULTS: For conformity index (CI), Co‐CRIM performed comparably to IMRT/VMAT but better than CRT. For gradient index (GI), Co‐CRIM was similar to IMRT/VMAT or CRT. For heterogeneity index (HI), Co‐CRIM was comparable to IMRT/VMAT, higher than CRT. The dosimetric results of spinal cord and lung with Co‐CRIM were better than CRT, comparable to IMRT, but inferior to VMAT. The MU resulted from Co‐CRIM was lower than IMRT/VMAT but higher than CRT. For plan verification γ passing rate, Co‐CRIM was higher than IMRT/VMAT, comparable to CRT. For planning time, Co‐CRIM was shorter than CRT or VMAT but similar to IMRT. CONCLUSIONS: The proposed Co‐CRIM technique on Pinnacle TPS is an effective planning technique for peripheral lung SBRT.
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spelling pubmed-86641472021-12-21 A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system Duan, YanHua Zhou, LiJun Wang, Hao Chen, Hua Gu, HengLe Shao, Yan Feng, AiHui Huang, Ying Fu, XiaoLong Yue, Ning Jeff Ma, Kui Kong, Qing Xu, ZhiYong J Appl Clin Med Phys Radiation Oncology Physics OBJECTIVES: This study attempts to explore a novel peripheral lung stereotactic body radiotherapy (SBRT) planning technique that can balance the pros and cons of three‐dimensional conformal radiotherapy (CRT) and intensity‐modulated radiation therapy (IMRT) / volumetric modulated arc therapy (VMAT). METHODS: Treatment plans were retrospectively designed based on CRT, IMRT, VMAT, and the proposed CRT‐IMRT‐combined (Co‐CRIM) techniques using Pinnacle treatment planning system (TPS) for 20 peripheral lung cancer patients. Co‐CRIM used an inverse optimization algorithm available in Pinnacle TPS. To develop a Co‐CRIM plan, the number of segments in each field was limited to one, the minimum segment area was set to the internal target volume (ITV), and the minimum monitor units (MU) of the segment was the quotient of fractional dose divided by twice the number of total fields. The performance of Co‐CRIM was then compared with other techniques. RESULTS: For conformity index (CI), Co‐CRIM performed comparably to IMRT/VMAT but better than CRT. For gradient index (GI), Co‐CRIM was similar to IMRT/VMAT or CRT. For heterogeneity index (HI), Co‐CRIM was comparable to IMRT/VMAT, higher than CRT. The dosimetric results of spinal cord and lung with Co‐CRIM were better than CRT, comparable to IMRT, but inferior to VMAT. The MU resulted from Co‐CRIM was lower than IMRT/VMAT but higher than CRT. For plan verification γ passing rate, Co‐CRIM was higher than IMRT/VMAT, comparable to CRT. For planning time, Co‐CRIM was shorter than CRT or VMAT but similar to IMRT. CONCLUSIONS: The proposed Co‐CRIM technique on Pinnacle TPS is an effective planning technique for peripheral lung SBRT. John Wiley and Sons Inc. 2021-10-26 /pmc/articles/PMC8664147/ /pubmed/34699670 http://dx.doi.org/10.1002/acm2.13461 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Duan, YanHua
Zhou, LiJun
Wang, Hao
Chen, Hua
Gu, HengLe
Shao, Yan
Feng, AiHui
Huang, Ying
Fu, XiaoLong
Yue, Ning Jeff
Ma, Kui
Kong, Qing
Xu, ZhiYong
A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system
title A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system
title_full A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system
title_fullStr A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system
title_full_unstemmed A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system
title_short A novel CRT‐IMRT‐combined (Co‐CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system
title_sort novel crt‐imrt‐combined (co‐crim) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664147/
https://www.ncbi.nlm.nih.gov/pubmed/34699670
http://dx.doi.org/10.1002/acm2.13461
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