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Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate

Proper regulation of microtubule (MT) dynamics is critical for cellular processes including cell division and intracellular transport. Plus-end tracking proteins (+TIPs) dynamically track growing MTs and play a key role in MT regulation. +TIPs participate in a complex web of intra- and inter- molecu...

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Detalles Bibliográficos
Autores principales: Wu, Yueh-Fu O., Bryant, Annamarie T., Nelson, Nora T., Madey, Alexander G., Fernandes, Gail F., Goodson, Holly V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664194/
https://www.ncbi.nlm.nih.gov/pubmed/34890409
http://dx.doi.org/10.1371/journal.pone.0260401