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TFEB Dependent Autophagy-Lysosomal Pathway: An Emerging Pharmacological Target in Sepsis

Sepsis is a life-threatening syndrome induced by aberrant host response towards infection. The autophagy-lysosomal pathway (ALP) plays a fundamental role in maintaining cellular homeostasis and conferring organ protection. However, this pathway is often impaired in sepsis, resulting in dysregulated...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Zheng, Xinchuan, Lu, Yongling, Chen, Qian, Zheng, Jiang, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664376/
https://www.ncbi.nlm.nih.gov/pubmed/34899355
http://dx.doi.org/10.3389/fphar.2021.794298

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