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Harnessing natural variation to identify cis regulators of sex-biased gene expression in a multi-strain mouse liver model

Sex differences in gene expression are widespread in the liver, where many autosomal factors act in tandem with growth hormone signaling to regulate individual variability of sex differences in liver metabolism and disease. Here, we compare hepatic transcriptomic and epigenetic profiles of mouse str...

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Detalles Bibliográficos
Autores principales: Matthews, Bryan J., Melia, Tisha, Waxman, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664386/
https://www.ncbi.nlm.nih.gov/pubmed/34752452
http://dx.doi.org/10.1371/journal.pgen.1009588