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Hodgkin’s Lymphoma in the Context of Psoriasis Vulgaris Treated With Immunosuppressive Therapy: A Case Report and Review of Literature

Psoriasis is a multisystemic chronic inflammatory immune-mediated disorder presenting with multiple clinical manifestations and comorbidities. Studies suggested a significant association between the incidence of malignancy including Hodgkin’s lymphoma and cutaneous T-cell lymphoma and malignancy-rel...

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Detalles Bibliográficos
Autores principales: Alali, Zainab, Al Ashour, Bayan H, Alrefaee, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664404/
https://www.ncbi.nlm.nih.gov/pubmed/34912631
http://dx.doi.org/10.7759/cureus.19490
Descripción
Sumario:Psoriasis is a multisystemic chronic inflammatory immune-mediated disorder presenting with multiple clinical manifestations and comorbidities. Studies suggested a significant association between the incidence of malignancy including Hodgkin’s lymphoma and cutaneous T-cell lymphoma and malignancy-related deaths in patients with psoriasis owing to the disease itself, the chronic inflammation, and the immunosuppressive or immunomodulatory effect of drugs. This case report is discussing the condition of an 18-year-old female, who has developed Hodgkin’s lymphoma after receiving immunosuppressive therapy in the context of psoriasis vulgaris flare-up.