Impaired Cognitive Function and Hippocampal Changes Following Chronic Diazepam Treatment in Middle-Aged Mice

Background: Gamma-aminobutyric acid (GABA) type A receptors are positively allosterically modulated by benzodiazepine binding, leading to a potentiated response to GABA. Diazepam (DZP, a benzodiazepine) is widely prescribed for anxiety, epileptic discharge, and insomnia, and is also used as a muscle...

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Detalles Bibliográficos
Autores principales: Furukawa, Tomonori, Nikaido, Yoshikazu, Shimoyama, Shuji, Masuyama, Nozomu, Notoya, Ayaka, Ueno, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664496/
https://www.ncbi.nlm.nih.gov/pubmed/34899279
http://dx.doi.org/10.3389/fnagi.2021.777404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664496/
https://www.ncbi.nlm.nih.gov/pubmed/34899279
http://dx.doi.org/10.3389/fnagi.2021.777404

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