N-Acetylcysteine (NAC) Inhibits Synthesis of IL-18 in Macrophage by Suppressing NLRP3 Expression to Reduce the Production of IFN-γ from NK Cells

BACKGROUND: N-Acetylcysteine (NAC) had exerted antioxidation and anti-inflammation effects on chronic obstructive pulmonary disease (COPD) patients. However, its effect in regulating interleukin- (IL-) 18 was not fully understood. This study was designed to evaluate the specific mechanism of NAC reg...

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Detalles Bibliográficos
Autores principales: Liu, Xiaopeng, Lu, Xufeng, Hu, Zhixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664516/
https://www.ncbi.nlm.nih.gov/pubmed/34899969
http://dx.doi.org/10.1155/2021/7596343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664516/
https://www.ncbi.nlm.nih.gov/pubmed/34899969
http://dx.doi.org/10.1155/2021/7596343

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