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ACT-1 Multicenter investigator-initiated registration-directed Phase 2 study of E7090 in subjects with advanced or recurrent solid tumors with fibroblast growth factor receptor (FGFR) gene alteration: FORTUNE trial
Background: Genetic alterations of FGFRs are known to play an important role in the proliferation, survival, and migration of cancer cells as well as tumor angiogenesis and drug resistance. E7090 is an orally available selective tyrosine kinase inhibitor for FGFR1-3. A global Phase 2 study of E7090...
Autores principales: | Takahashi, Masamichi, Chiba, Yohei, Sudo, Kazuki, Kojima, Yuki, Okuma, Hitomi, Kohsaka, Shinji, Ichimura, Masahiko, Okita, Natsuko, Nakamura, Kenichi, Machida, Ryunosuke, Kinoshita, Ichiro, Takahashi, Masanobu, Matsubara, Junichi, Kusaba, Hitoshi, Yonemori, Kan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664618/ http://dx.doi.org/10.1093/noajnl/vdab159.033 |
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