Depletion of NK6 Homeobox 3 (NKX6.3) causes gastric carcinogenesis through copy number alterations by inducing impairment of DNA replication and repair regulation

Genomic stability maintenance requires correct DNA replication, chromosome segregation, and DNA repair, while defects of these processes result in tumor development or cell death. Although abnormalities in DNA replication and repair regulation are proposed as underlying causes for genomic instabilit...

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Detalles Bibliográficos
Autores principales: Yoon, Jung Hwan, Eun, Jung Woo, Ashktorab, Hassan, Smoot, Duane T., Kim, Jeong kyu, Nam, Suk Woo, Park, Won Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664813/
https://www.ncbi.nlm.nih.gov/pubmed/34893582
http://dx.doi.org/10.1038/s41389-021-00365-4

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