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Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins

Combining several innate immune peptides into a single recombinant antimicrobial and immunomodulatory polypeptide has been recently demonstrated. However, the versatility of the multidomain design, the role that each domain plays and how the sequence edition of the different domains affects their fi...

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Detalles Bibliográficos
Autores principales: Roca-Pinilla, Ramon, Holani, Ravi, López-Cano, Adrià, Saubi, Cristina, Baltà-Foix, Ricardo, Cobo, Eduardo R., Garcia-Fruitós, Elena, Arís, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664906/
https://www.ncbi.nlm.nih.gov/pubmed/34893661
http://dx.doi.org/10.1038/s41598-021-03220-z