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Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins
Combining several innate immune peptides into a single recombinant antimicrobial and immunomodulatory polypeptide has been recently demonstrated. However, the versatility of the multidomain design, the role that each domain plays and how the sequence edition of the different domains affects their fi...
Autores principales: | Roca-Pinilla, Ramon, Holani, Ravi, López-Cano, Adrià, Saubi, Cristina, Baltà-Foix, Ricardo, Cobo, Eduardo R., Garcia-Fruitós, Elena, Arís, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664906/ https://www.ncbi.nlm.nih.gov/pubmed/34893661 http://dx.doi.org/10.1038/s41598-021-03220-z |
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