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Exploiting a Y chromosome-linked Cas9 for sex selection and gene drive

CRISPR-based genetic engineering tools aimed to bias sex ratios, or drive effector genes into animal populations, often integrate the transgenes into autosomal chromosomes. However, in species with heterogametic sex chromsomes (e.g. XY, ZW), sex linkage of endonucleases could be beneficial to drive...

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Detalles Bibliográficos
Autores principales:	Gamez, Stephanie, Chaverra-Rodriguez, Duverney, Buchman, Anna, Kandul, Nikolay P., Mendez-Sanchez, Stelia C., Bennett, Jared B., Sánchez C., Héctor M., Yang, Ting, Antoshechkin, Igor, Duque, Jonny E., Papathanos, Philippos A., Marshall, John M., Akbari, Omar S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664916/ https://www.ncbi.nlm.nih.gov/pubmed/34893590 http://dx.doi.org/10.1038/s41467-021-27333-1

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