CXCR4 blockade reduces the severity of murine heart allograft rejection by plasmacytoid dendritic cell-mediated immune regulation

Allograft-specific regulatory T cells (T(reg) cells) are crucial for long-term graft acceptance after transplantation. Although adoptive T(reg) cell transfer has been proposed, major challenges include graft-specificity and stability. Thus, there is an unmet need for the direct induction of graft-sp...

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Detalles Bibliográficos
Autores principales: Fu, Jian, Lehmann, Christian H. K., Wang, Xinning, Wahlbuhl, Mandy, Allabauer, Ida, Wilde, Benjamin, Amon, Lukas, Dolff, Sebastian, Cesnjevar, Robert, Kribben, Andreas, Woelfle, Joachim, Rascher, Wolfgang, Hoyer, Peter F., Dudziak, Diana, Witzke, Oliver, Hoerning, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664946/
https://www.ncbi.nlm.nih.gov/pubmed/34893663
http://dx.doi.org/10.1038/s41598-021-03115-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664946/
https://www.ncbi.nlm.nih.gov/pubmed/34893663
http://dx.doi.org/10.1038/s41598-021-03115-z

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