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Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine

PURPOSE OF REVIEW: The purpose of this review is to discuss the available evidence and therapeutic considerations for intravenous drug therapy for refractory chronic migraine. RECENT FINDINGS: In carefully monitored settings, the inpatient administration of intravenous lidocaine and ketamine can be...

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Autores principales: Mojica, Jeffrey J., Schwenk, Eric S., Lauritsen, Clinton, Nahas, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665315/
https://www.ncbi.nlm.nih.gov/pubmed/34894295
http://dx.doi.org/10.1007/s11916-021-00992-x
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author Mojica, Jeffrey J.
Schwenk, Eric S.
Lauritsen, Clinton
Nahas, Stephanie J.
author_facet Mojica, Jeffrey J.
Schwenk, Eric S.
Lauritsen, Clinton
Nahas, Stephanie J.
author_sort Mojica, Jeffrey J.
collection PubMed
description PURPOSE OF REVIEW: The purpose of this review is to discuss the available evidence and therapeutic considerations for intravenous drug therapy for refractory chronic migraine. RECENT FINDINGS: In carefully monitored settings, the inpatient administration of intravenous lidocaine and ketamine can be successful in treating refractory chronic migraine. SUMMARY: Many patients with refractory chronic migraine have experienced treatment failure with the Raskin protocol. The use of aggressive inpatient infusion therapy consisting of intravenous lidocaine or ketamine, along with other adjunctive medications, has become increasingly common for these patients when all other treatments have failed. There is a clear need for prospective studies in this population comprised of patients who have largely been excluded from other studies.
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spelling pubmed-86653152021-12-14 Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine Mojica, Jeffrey J. Schwenk, Eric S. Lauritsen, Clinton Nahas, Stephanie J. Curr Pain Headache Rep Anesthetic Techniques in Pain Management (D Wang, Section Editor) PURPOSE OF REVIEW: The purpose of this review is to discuss the available evidence and therapeutic considerations for intravenous drug therapy for refractory chronic migraine. RECENT FINDINGS: In carefully monitored settings, the inpatient administration of intravenous lidocaine and ketamine can be successful in treating refractory chronic migraine. SUMMARY: Many patients with refractory chronic migraine have experienced treatment failure with the Raskin protocol. The use of aggressive inpatient infusion therapy consisting of intravenous lidocaine or ketamine, along with other adjunctive medications, has become increasingly common for these patients when all other treatments have failed. There is a clear need for prospective studies in this population comprised of patients who have largely been excluded from other studies. Springer US 2021-12-11 2021 /pmc/articles/PMC8665315/ /pubmed/34894295 http://dx.doi.org/10.1007/s11916-021-00992-x Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Anesthetic Techniques in Pain Management (D Wang, Section Editor)
Mojica, Jeffrey J.
Schwenk, Eric S.
Lauritsen, Clinton
Nahas, Stephanie J.
Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine
title Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine
title_full Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine
title_fullStr Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine
title_full_unstemmed Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine
title_short Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic Migraine
title_sort beyond the raskin protocol: ketamine, lidocaine, and other therapies for refractory chronic migraine
topic Anesthetic Techniques in Pain Management (D Wang, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665315/
https://www.ncbi.nlm.nih.gov/pubmed/34894295
http://dx.doi.org/10.1007/s11916-021-00992-x
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