Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories

BACKGROUND: Detection of the pathological and disease-associated alpha-synuclein (αSyn(D)) in the brain is required to formulate the definitive diagnosis of multiple system atrophy (MSA) and Parkinson’s disease (PD). We recently showed that αSyn(D) can be detected in the olfactory mucosa (OM) of MSA...

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Detalles Bibliográficos
Autores principales: Bargar, Connor, De Luca, Chiara Maria Giulia, Devigili, Grazia, Elia, Antonio Emanuele, Cilia, Roberto, Portaleone, Sara Maria, Wang, Wen, Tramacere, Irene, Bistaffa, Edoardo, Cazzaniga, Federico Angelo, Felisati, Giovanni, Legname, Giuseppe, Di Fonzo, Alessio, Xu, Rong, Gunzler, Steven Alexander, Giaccone, Giorgio, Eleopra, Roberto, Chen, Shu Guang, Moda, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665327/
https://www.ncbi.nlm.nih.gov/pubmed/34895275
http://dx.doi.org/10.1186/s13024-021-00491-y

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