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Soluble amyloid-beta isoforms predict downstream Alzheimer’s disease pathology

BACKGROUND: Changes in soluble amyloid-beta (Aβ) levels in cerebrospinal fluid (CSF) are detectable at early preclinical stages of Alzheimer’s disease (AD). However, whether Aβ levels can predict downstream AD pathological features in cognitively unimpaired (CU) individuals remains unclear. With thi...

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Detalles Bibliográficos
Autores principales: Povala, Guilherme, Bellaver, Bruna, De Bastiani, Marco Antônio, Brum, Wagner S., Ferreira, Pamela C. L., Bieger, Andrei, Pascoal, Tharick A., Benedet, Andrea L., Souza, Diogo O., Araujo, Ricardo M., Zatt, Bruno, Rosa-Neto, Pedro, Zimmer, Eduardo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665586/
https://www.ncbi.nlm.nih.gov/pubmed/34895338
http://dx.doi.org/10.1186/s13578-021-00712-3