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Genome-wide methylation patterns in Marfan syndrome

BACKGROUND: Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the Fibrillin-1 gene (FBN1). Here, we undertook the first epigenome-wide association study (EWAS) in patients with MFS aiming at identifying DNA methylation loci associated with MFS phenotypes that may shed ligh...

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Detalles Bibliográficos
Autores principales:	van Andel, Mitzi M., Groenink, Maarten, van den Berg, Maarten P., Timmermans, Janneke, Scholte, Arthur J. H. A., Mulder, Barbara J. M., Zwinderman, Aeilko H., de Waard, Vivian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665617/ https://www.ncbi.nlm.nih.gov/pubmed/34895303 http://dx.doi.org/10.1186/s13148-021-01204-4

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