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Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas
Primary spinal cord tumors contribute to ≤ 10% of central nervous system tumors in individuals of pediatric or adolescent age. Among intramedullary tumors, spinal ependymomas make up ~ 30% of this rare tumor population. A twelve-year-old male presented with an intradural, extramedullary mass occupyi...
Autores principales: | Shatara, Margaret, Schieffer, Kathleen M., Klawinski, Darren, Thomas, Diana L., Pierson, Christopher R., Sribnick, Eric A., Jones, Jeremy, Rodriguez, Diana P., Deeg, Carol, Hamelberg, Elizabeth, LaHaye, Stephanie, Miller, Katherine E., Fitch, James, Kelly, Benjamin, Leraas, Kristen, Pfau, Ruthann, White, Peter, Magrini, Vincent, Wilson, Richard K., Mardis, Elaine R., Abdelbaki, Mohamed S., Finlay, Jonathan L., Boué, Daniel R., Cottrell, Catherine E., Ghasemi, David R., Pajtler, Kristian W., Osorio, Diana S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665631/ https://www.ncbi.nlm.nih.gov/pubmed/34895332 http://dx.doi.org/10.1186/s40478-021-01296-2 |
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