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Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas

Primary spinal cord tumors contribute to ≤ 10% of central nervous system tumors in individuals of pediatric or adolescent age. Among intramedullary tumors, spinal ependymomas make up ~ 30% of this rare tumor population. A twelve-year-old male presented with an intradural, extramedullary mass occupyi...

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Detalles Bibliográficos
Autores principales: Shatara, Margaret, Schieffer, Kathleen M., Klawinski, Darren, Thomas, Diana L., Pierson, Christopher R., Sribnick, Eric A., Jones, Jeremy, Rodriguez, Diana P., Deeg, Carol, Hamelberg, Elizabeth, LaHaye, Stephanie, Miller, Katherine E., Fitch, James, Kelly, Benjamin, Leraas, Kristen, Pfau, Ruthann, White, Peter, Magrini, Vincent, Wilson, Richard K., Mardis, Elaine R., Abdelbaki, Mohamed S., Finlay, Jonathan L., Boué, Daniel R., Cottrell, Catherine E., Ghasemi, David R., Pajtler, Kristian W., Osorio, Diana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665631/
https://www.ncbi.nlm.nih.gov/pubmed/34895332
http://dx.doi.org/10.1186/s40478-021-01296-2

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