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MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model

BACKGROUND: Previous studies have confirmed that the microglial activation and subsequent inflammatory responses in the trigeminal nucleus caudalis (TNC) are involved in the central sensitization of chronic migraine (CM). MicroRNA-155-5p has been shown to modulate the polarization of microglia and p...

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Detalles Bibliográficos
Autores principales: Wen, Qianwen, Wang, Yunfeng, Pan, Qi, Tian, Ruimin, Zhang, Dunke, Qin, Guangcheng, Zhou, Jiying, Chen, Lixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665643/
https://www.ncbi.nlm.nih.gov/pubmed/34893074
http://dx.doi.org/10.1186/s12974-021-02342-5

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