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MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model
BACKGROUND: Previous studies have confirmed that the microglial activation and subsequent inflammatory responses in the trigeminal nucleus caudalis (TNC) are involved in the central sensitization of chronic migraine (CM). MicroRNA-155-5p has been shown to modulate the polarization of microglia and p...
Autores principales: | Wen, Qianwen, Wang, Yunfeng, Pan, Qi, Tian, Ruimin, Zhang, Dunke, Qin, Guangcheng, Zhou, Jiying, Chen, Lixue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665643/ https://www.ncbi.nlm.nih.gov/pubmed/34893074 http://dx.doi.org/10.1186/s12974-021-02342-5 |
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