Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar

Maturity‐onset diabetes of young (MODY) is an autosomal dominant genetic disorder that causes insulin deficiency without autoimmunity. We present the first family with pancreatic duodenal homeobox 1 (PDX1) mutation causing diabetes from Qatar. Routine genetic screening of all antibody‐negative diabe...

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Autores principales: Haris, Basma, Mohammed, Idris, Syed, Najeeb, Fakhro, Khalid, Hussain, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665722/
https://www.ncbi.nlm.nih.gov/pubmed/34938542
http://dx.doi.org/10.1002/ccr3.5141
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author Haris, Basma
Mohammed, Idris
Syed, Najeeb
Fakhro, Khalid
Hussain, Khalid
author_facet Haris, Basma
Mohammed, Idris
Syed, Najeeb
Fakhro, Khalid
Hussain, Khalid
author_sort Haris, Basma
collection PubMed
description Maturity‐onset diabetes of young (MODY) is an autosomal dominant genetic disorder that causes insulin deficiency without autoimmunity. We present the first family with pancreatic duodenal homeobox 1 (PDX1) mutation causing diabetes from Qatar. Routine genetic screening of all antibody‐negative diabetic patients with diabetes should be offered to avoid misdiagnosis.
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spelling pubmed-86657222021-12-21 Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar Haris, Basma Mohammed, Idris Syed, Najeeb Fakhro, Khalid Hussain, Khalid Clin Case Rep Case Report Maturity‐onset diabetes of young (MODY) is an autosomal dominant genetic disorder that causes insulin deficiency without autoimmunity. We present the first family with pancreatic duodenal homeobox 1 (PDX1) mutation causing diabetes from Qatar. Routine genetic screening of all antibody‐negative diabetic patients with diabetes should be offered to avoid misdiagnosis. John Wiley and Sons Inc. 2021-12-11 /pmc/articles/PMC8665722/ /pubmed/34938542 http://dx.doi.org/10.1002/ccr3.5141 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Haris, Basma
Mohammed, Idris
Syed, Najeeb
Fakhro, Khalid
Hussain, Khalid
Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar
title Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar
title_full Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar
title_fullStr Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar
title_full_unstemmed Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar
title_short Maturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar
title_sort maturity‐onset diabetes of the young (mody) due to pdx1 mutation in a sib‐pair diabetes family from qatar
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665722/
https://www.ncbi.nlm.nih.gov/pubmed/34938542
http://dx.doi.org/10.1002/ccr3.5141
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AT syednajeeb maturityonsetdiabetesoftheyoungmodyduetopdx1mutationinasibpairdiabetesfamilyfromqatar
AT fakhrokhalid maturityonsetdiabetesoftheyoungmodyduetopdx1mutationinasibpairdiabetesfamilyfromqatar
AT hussainkhalid maturityonsetdiabetesoftheyoungmodyduetopdx1mutationinasibpairdiabetesfamilyfromqatar

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